Research on Noni

HAWAIIAN HEALTH OHANA LLC NONI FRUIT LEATHER

RESEARCH ON NONI There's been a newly released outburst in how much research being carried out into the features and biochemicals belonging to the Noni fruit, as a result of testimonials and worldwide interest occurring ever since the exposure of Noni to the more technologically sophisticated countries. There are presently many laboratory and clinical tests showing with positive outcomes the many uses the ancient healers ascribed to this particular plant, along with discovering new strategies to utilize the biochemistry of Noni. Below are listed many of the inspections which have been published.

Thank you to all who are doing this vital work!!

1. Cytotoxicity of Water and Ethanol extracts of Morinda citrifolia (L.) Against Normal Epithelial and Breast Cancer Lines – A. Johnson, S.T. Hemscheidt, W.K. Csiszar, Proceedings, 2002 Hawai’I Noni Conference

2. Anti-cancer Activity of Noni Fruit Juice Against Tumors in Mice – Eiichi Furusawa, M.D., Ph.D., Proceedings, 2002 Hawai’I Noni Conference

3. Induction of normal phenotypes in ras-transformed cells by damnacanthal from Morinda citrifolia – T. Hiramatsu, M. Imoto, K. Umezawa, Cancer Letters 73(2-3):161-6; 1993

4. Antitumor Studies of a Traditional Hawaiian Medicinal Plant, Morinda citrifolia (Noni), In Vitro and In Vivo – Anne Hirazumi, Doctoral dissertation, summary: 1997

5. An immunomodulatory polysaccharide-rich substance from the fruit juice of Morinda citrifolia (noni) with anti-tumor activity – E. Furusawa, A. Hirazumi, Phytotherapy Research 13:380-7: 1999

6. Immunomodulation contributes to anti-cancer activity of Morinda citrifolia (noni) fruit juice – A. Hirazumi, E. Furusawa, S.C. Chou, Y. Hokama, Prodeedings of the Western Pharmaceutical Society 39:7-9; 1996

7. Anticancer activity of Morinda citrifolia (noni) on intraperitoneally implanted Lewis Lung carcinoma in syngenic mice– A. Hirazumi, E. Furusawa, S.C. Chou, Y. Hokama, Proceedings of the Western Pharmaceutical Society 37:145-6;1994

8. Isolation, identification and biosynthesis of anthraquinones in cell suspension cultures of Morinda citrifolia – E. Leistner, Planta Medica Supplement 214-224; 1975

9. Some Chemical Constituents of Morinda citrifolia (noni) – O.Levand, H.O. Larson, :Planta medica 36; 186-87;1979

10. Two novel glycosides from fruits of Morinda citrifolia (noni) inhibit AP-1 transactivation and cell transformation in the mouse epidermal JB6 cell line – G. Liu, A. Bode, W.Y. Ma, S. Sang, C.T. Ho, Z. Dong, Cancer Research 61:5749-56; 2001

11. The effect of phosphoramides on the growth of a variety of mouse and rat tumors – K. Sugiura, C.C. Stock, Cancer Research 15:38-51; 1955

12. Novel trisaccharide fatty acid ester identified from the fruits of Morinda citrifolia (Noni) – M. Wang, H. Kikusaki, L. Csiszar, C,.D. Boyd, A. Maunakea, S.F. Fong, G. Ghai, R.T. Rosen, N. Nakatani, C.T. Ho, Journal of Agricultural Food Chemistry 47:4880-2; 1999

13. Novel glycosides from noni (Morinda citrifolia), M. Wang, H. Kikusaki, Y. Jin, N. Nakatani, N. Zhu, L. Csiszar, C.D. Boyd, R.T. Rosen, G. Ghai, C.T. Ho, Journal of Natural Products 63:1182-3; 2000

14. Analgesic and behavioral effects of Morinda citrifolia – C. Younos, A. Rolland, J. Fleurentin, M.C. Lanhers, R. Misslin, F. Mortier, Planta Medica 56(5):430-4; 1990

15. Anthraquinone production by cell suspension cultures of Morinda citrifolia – M.H. Zenk, H. el-Shagi, U. Schulte, Planta Medica Supplement 79-101

16. A New Selective COX-2 Inhibitor: Morinda Citrifolia (NONI) – C.X. Su, C.J. Jensen, M.Y. Wang, J.W. Fritz, S. Jensen, Dep’t of Pathology, College of Medicine, Rockford Illinois

17. Inhibition of the oligosaccharides extracted from Morinda officinalis, a Chinese traditional herbal medicine, on the corticosterone induced apoptosis in PC12 cells – Y.F. Li, Z.H. Gong, M. Yang, Y.M. Zhou, Z.P. Luo, Life Sci 2003 Jan 10;72(8):933-42

18. Preliminary investigation of the anti-inflammatory properties of an aqueous extract from Morinda citrifolia (noni) – M.L. McKoy, E.A. Thomas, O.R. Simon., Proc West Pharmacol Soc 2002;45:76-8

19. Cancer preventive effect of Morinda citrifolia (Noni) – M.Y. Wang, C. Su, Ann. N Y Acad Sci. 2001 Dec;952:161-8

20. From Polynesian Healers to Health Food Stores: Changing Ethnopharmacology of Morinda citrifolia - Will McClatchey, Journal of Integrative Cancer Therapy. 1(2):110-120; 2002

-a number of these are viewable online, from websites including www.PubMed.com, or through search engines